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    請使用永久網址來引用或連結此文件: https://irlib.pccu.edu.tw/handle/987654321/48793


    題名: Ubiquinone Supplementation with 300 mg on Glycemic Control and Antioxidant Status in Athletes: A Randomized, Double-Blinded, Placebo-Controlled Trial
    作者: Ho, CC (Ho, Chien-Chang)
    Chang, PS (Chang, Po-Sheng)
    Chen, HW (Chen, Hung-Wun)
    Lee, PF (Lee, Po-Fu)
    Chang, YC (Chang, Yun-Chi)
    Tseng, CY (Tseng, Ching-Yu)
    Lin, PT (Lin, Ping-Ting)
    貢獻者: 運教所
    關鍵詞: ubiquinone supplementation
    athletes
    glycaemia
    antioxidant
    sport nutrition
    日期: 2020-09
    上傳時間: 2020-11-06 14:10:42 (UTC+8)
    摘要: The aim of this study is to investigate the glycemic profile, oxidative stress, and antioxidant capacity in athletes after 12 weeks of ubiquinone supplementation. It was a double-blinded, randomized, parallel, placebo-controlled study. Thirty-one well-trained college athletes were randomly assigned to ubiquinone (300 mg/d, n = 17) or placebo group (n = 14). The glycemic profile [fasting glucose, glycated hemoglobin (HbA1c), homeostatic model assessment-insulin resistance (HOMA-IR), quantitative insulin sensitivity check index (QUICKI)], plasma and erythrocyte malondialdehyde (MDA), total antioxidant capacity (TAC), and ubiquinone status were measured. After supplementation, the plasma ubiquinone concentration was significantly increased (p < 0.05) and the level of erythrocyte MDA was significantly lower in the ubiquinone group than in the placebo group (p < 0.01). There was a significant correlation between white blood cell (WBC) ubiquinone and glycemic parameters [HbA1c, r = -0.46, p < 0.05; HOMA-IR, r = -0.67, p < 0.01; QUICKI, r = 0.67, p < 0.01]. In addition, athletes with higher WBC ubiquinone level (>= 0.5 nmol/g) showed higher erythrocyte TAC and QUICKI and lower HOMA-IR. In conclusion, we demonstrated that athletes may show a better antioxidant capacity with higher ubiquinone status after 12 weeks of supplementation, which may further improve glycemic control.
    關聯: ANTIOXIDANTS 卷冊: 9 期: 9 文獻號碼: 823
    顯示於類別:[運動教練研究所] 期刊論文

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