文化大學機構典藏 CCUR:Item 987654321/3030
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    题名: Schizarin B, C, D, and E, four new lignans from Kadsura matsudai and their antihepatitis activities
    作者: Kuo YH;Li SY;Huang RL;Wu MD;Huang HC;Lee KH
    贡献者: 化學系
    日期: 2001
    上传时间: 2009-12-14 10:34:26 (UTC+8)
    摘要: Bioassay-directed fractionation of ethanolic extract of Kadsura matsudai Hayata has resulted in the isolation of four novel C-18 dibenzocyclooctadiene lignans, schizarin B (1), schizarin C (2), schizarin D (3), and schizarin E (4). Schizarin B (1) showed moderate to strong activity for antihepatitis in both anti-HBsAg and anti-HBeAg assays, and 3 and 4 also were active in the latter assay. Compounds 1-4 were inactive in vitro against HIV replication in H9 lymphocytes. All new structures were elucidated using spectral analysis. Their structural elucidation by spectral and structure-activity relationships is also discussed.
    關聯: JOURNAL OF NATURAL PRODUCTS Volume: 64 Issue: 4 Pages: 487-490
    显示于类别:[化學系所] 期刊論文

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