A Meta-Analysis of Comparing Intermittent Epidural Boluses and Continuous Epidural Infusion for Labor Analgesia

CCUR > College of Natural Science and Engineering > College of Science > Department of Applied Mathematics > journal articles > Item 987654321/48827

Please use this identifier to cite or link to this item: https://irlib.pccu.edu.tw/handle/987654321/48827

Title:	A Meta-Analysis of Comparing Intermittent Epidural Boluses and Continuous Epidural Infusion for Labor Analgesia
Authors:	Tzeng, IS (Tzeng, I-Shiang) Kao, MC (Kao, Ming-Chang) Pan, PT (Pan, Po-Ting) Chen, CT (Chen, Chu-Ting) Lin, HY (Lin, Han-Yu) Hsieh, PC (Hsieh, Po-Chun) Kuo, CY (Kuo, Chan-Yen) Hsieh, TH (Hsieh, Tsung-Han) Kung, WM (Kung, Woon-Man) Cheng, CH (Cheng, Chu-Hsuan) Chen, KH (Chen, Kuo-Hu)
Contributors:	應數系
Keywords:	continuous epidural infusion (CEI) intermittent epidural bolus (IEB) labor analgesia meta-analysis
Date:	2020-10
Issue Date:	2020-11-24 13:41:30 (UTC+8)
Abstract:	With the development of medical equipment and techniques in labor anesthesia, it is a major issue to investigate the risks and treatment effects among techniques such as continuous epidural infusion (CEI) and intermittent epidural bolus (IEB). However, there is a controversial result regarding two techniques. This study was conducted through meta-analysis of randomized controlled trials (RCTs) for labor analgesia between the CEI and IEB techniques. The pooled results were presented as weighted mean differences (WMDs) together with 95% confidence intervals (CIs) and odds ratios (ORs) together with 95% CIs, respectively. Eleven RCTs were included in this meta-analysis. Four hundred sixty-five parturients accepted CEI, whereas 473 parturients accepted IEB labor analgesia. Elven identified low- risk bias studies were recruited for meta-analysis. The results presented no statistical difference in cesarean delivery rate between IEB and CEI (OR, 0.96; 95% CI, 0.67-1.37) and duration of second stage of labor (WMD, -3.82 min; 95% CI, -8.28 to 0.64). IEB had statistically significant lessened risk of instrumental delivery (OR, 0.59; 95% CI, 0.39-0.90) and for the use in local anesthetic (WMD, -1.71 mg bupivacaine equivalents per hour; 95% CI, -1.88 and -1.55). Accepted IEB had a higher score of maternal satisfaction (WMD, -6.95 mm; 95% CI, -7.77 to -6.13). Based on evidence, IEB showed a greater benefit for slightly reducing the use in local anesthetic, reduced risk of instrumental delivery, and improved maternal satisfaction for the requirement of labor epidural analgesia for healthy women. In the future, more studies need to be conducted to practice the IEB regimen and explore its influence on labor analgesia.
Relation:	INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 卷冊: 17 期: 19 文獻號碼: 7082
Appears in Collections:	[Department of Applied Mathematics] journal articles

Files in This Item:

File	Description	Size	Format
index.html		0Kb	HTML	209	View/Open

View Licence

Loading...