目的：探討藥物合併團體認知行為治療對強迫症患者的治療效果，是否較單一藥物治療來得顯著。方法：採準實驗設計進行，經臺北市立聯合醫院人體試驗委員會審核通過後，邀請21位合格受試者參加，再依報名順序分派組別。優先報名的11位受試者，納入「實驗組」（合併藥物與團體認知行為治療）。後續報名的10位受試者，則納入「控制組」（僅單一藥物治療）。使用工具包括：耶魯—布朗強迫症量表（Y-BOCS）、漢氏憂鬱量表（HAM-D）、漢氏焦慮量表（HAM-A）、生活品質問卷（WHOQOL）。結果：顯示實驗組在強迫症嚴重度、憂鬱程度、焦慮程度及生活品質等向度的前－後測分數差異上，均顯著高於控制組。結論：研究證實藥物合併團體認知行為治療對強迫症患者的治療效果，顯著較單一藥物治療來得有效。藉此，提出具體建議，供強迫症臨床治療人員及未來相關研究之參考。
Objectives: This study aimed to assess if the treatment outcome of cognitive-behavioral group psychotherapy (CBGP) with medication is better than medication treatment only in outpatients with obsessive-compulsive disorder (OCD). Methods: We adopted a quasi-experimental design (the pretestposttest nonequivalent) in this study, and the research protocol was approved by institutional review board of our hospital. A total of 21 subjects were enrolled in this study. The first 11 subjects were assigned to experimental group attending 11 sessions of CBGP with medication, while the rest of the 10 subjects were assigned to control group for medication treatment only (compensational CBGP was carried out after this study). The Yale-Brown Obsessive-Compulsive Scale, Hamilton Depression Rating Scale, Hamilton Anxiety Scale, and WHO Quality of Life were used for clinical assessments of the research subjects. Results: The statistical results showed that CBGP with medication had better treatment outcome than medication treatment only in the OCD patients. Conclusion: Based on these findings, we propose a few practical suggestions for treating OCD patients and research.
