A novel C-methylated biflavone, taiwanhomoflavone-B (1), together with known compounds, 7,4',7-tri-O-methylamentollavone, 6-C-methyinaringenin and apigenin-7-O-beta-glucoside were isolated from an ethanolic extract of Cephalotaxus wilsoniana. The structure of 1 was elucidated on the basis of spectroscopic analysis. Taiwanhomoflavone-B is cytotoxic with ED50, values of 3.8 and 3.5 mug/ml, against KB oral epidermoid carcinoma and Hepa-3B hepatoma cells, respectively.
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CHEMICAL & PHARMACEUTICAL BULLETIN Volume: 50 Issue: 12 Pages: 1607-1608
