太極拳運動介入對異位性皮膚炎學童身體免疫球蛋白IgE的影響

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Title:	太極拳運動介入對異位性皮膚炎學童身體免疫球蛋白IgE的影響 The Effect of Tai Chi Exercise Intervention on the Serum Levels of IgE in School-aged Patients with Atopic Dermatitis
Authors:	張煜昭張曉昀李再立林琬鈞鄭世忠
Contributors:	文化體育學刊
Keywords:	太極拳異位性皮膚炎 IL-4 IFN-γ Atopic dermatitis IFN-γ IL-4 cytokines skin
Date:	2012-06
Issue Date:	2014-11-25 17:25:56 (UTC+8)
Abstract:	Purpose: Atopic dermatitis (AD) is a skin disease associated with prolonged unhealed wounds and infections due to repetitive scratching, which commonly begins in childhood. In patients with AD, the serum IgE levels are positively correlated with symptoms of the disease. This study aimed to investigate the effect of Tai-Chi exercise on the serum IgE levels in school-aged children with AD. Method: Eight elementary school children with AD aged 6 to 12 years were included in this study. The participants executed on-hour Tai-Chi exercise session for five times per week for eight weeks without medication during the study. Blood samples were taken before and after exercise intervention for each participant. The serum levels of IgE and other Th cytokines (IFN-γ, IL-4) that may modulate IgE synthesis were measured by an allergic Immunoanalyser (Pharmacia Unicap 100). Data were analyzed by paired T-test using SPSS17.0 software, the significance level was set at α=.05. Results: The results showed a significant difference (p＜ 0.05) in the serum levels of IgE between pre-exercise (mean ±SD, 589.1±370.8KU/L) and post-exercise (528.1±383.9KU/L). Conclusion: This study demonstrated a trend that Tai-Chi exercise might be associated with lower serum IgE levels, suggesting a beneficial effect of the exercise on school-aged patients with AD.
Relation:	文化體育學刊； 14 期 (2012 / 06 / 01) ， P57 - 65
Appears in Collections:	[Department of Physical Education] Journal

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