文化大學機構典藏 CCUR:Item 987654321/21502
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    題名: 低氧運動訓練對坐式生活型態者血管內皮生長因子之影響
    The Influence of Hypoxic Training on Cardiovascular Risk Factors of Sedentary People
    作者: 林正常
    貢獻者: 運教所
    關鍵詞: 低氧訓練
    血管內皮生長因子
    代謝症侯群
    hypoxic training
    vascular endothelial growth factor
    metabolic syndrome
    日期: 2009-08
    上傳時間: 2012-02-23 10:52:07 (UTC+8)
    摘要: 高地訓練是競技選手在重要比賽前的熱門訓練方式。近年來人工低氧艙的發明,節省了傳統高地訓練費時費力的缺點,許多研究以人工低氧艙進行間歇式低氧訓練(Intermittent Hypoxic Training, IHT),亦有正面效果出現。然而,低氧環境曝露時間長短與運動強度的搭配,效果目前似乎未有定論。低氧誘發因子-1(HIF-1)為體內調節血管內皮生長因子(VEGF)重要環節,低氧環境造成人體細胞缺氧狀態,有可能促進血管內皮細胞修補作用。因此,本研究目的在透過不同組合之IHT,研究坐式生活型態者的心血管危險因子的訓練效果。方法:招募20 歲以上無規律運動習慣、BMI 大於25 以上或體脂率大於30%以上者共30 名男性。將通過篩選條件的受試者分為三組,氧氣相對濃度16%組、14%組、對照組(正常氧氣濃度20.70-20.93%),並於訓練前進行基本心肺適能與血液生化檢驗。人工常壓低氧艙以個人50%V ‧ O2max 運動強度執行健走運動30 分鐘與動態恢復30 分鐘,共計60 分鐘。每週三次健走運動訓練,共 12 週。於訓練期第3、6、9、12 週與訓練後第1、3 週,進行攝氧量測試與採血檢驗。以混合設計二因子變異數分析法比較各組訓練前、訓練期第3、6、9、12 週結束與追蹤期第1、3 週時,在最大攝氧量、血管內生長因子、總膽固醇、三酸甘油酯數據之差異。本研究期能找出較適切的IHT 模式。
    Altitude training is a popular conditioning method for athletes to improve endurance performance. Recently, many researches indicated intermittent hypoxic training (IHT) could increase athlete performance by economical and time-efficient artificial hypoxic chamber. However, the proper IHT duration and intensity are still a mystery. Hypoxia inducible factor-1(HIF-1) regulated vascular endothelial growth factor (VGEF) to induce vascular reparation process under hypoxia environment. Purpose: to investigate the influence of intermittent hypoxic training on sedentary people with cardiovascular risk factors by artificial hypoxic chamber. Methods: 30 sedentary lifestyle males characteristic of high BMI (>25%) or body fat percentage (>30%), divided into three groups i.e. FIO2 16%, FIO2 14% and control (20.70-20.93%) groups. All subjects requiredV ‧ O2max test and blood routine examination before IHT training. IHT protocol will be set at 50%V ‧ O2max of brisk walking on treadmill for 30 minutes then followed by a 30 minutes of cool down period, 3 times a week for total 12 weeks. There are 6 times ofV ‧ O2max tests and blood routine examinations performed at the end of 3rd, 6th, 9th and 12th week during IHT training, and 1st and 3rd week post-training, respectively. The mix-designed two-wayANOVA method will be applied to compare the difference among three groups forV ‧ O2max, VEGF, total cholesterol and triglycerides.We expect to find a better artificial IHT training module at the conclusion of this research.
    顯示於類別:[運動教練研究所] 研究計畫

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